UVEDEXAVET
Injectable Solution
Dexamethasone 2 mg/ml
Composition:
Each 1 ml contains:
Dexamethasone (as Sodium Phosphate) 2 mg
Dexamethasone (as Sodium Phosphate) 2 mg
Properties:
UVEDEXAVET contains the sodium phosphate ester of dexamethasone, a fluoro-methyl derivative of prednisolone, which is a potent glucocorticoid with minimal mineralocorticoid activity. Dexamethasone has ten to twenty times the anti-inflammatory activity of prednisolone. Following intramuscular injection this soluble ester of dexamethasone is rapidly absorbed and hydrolyzed to the parent alcohol giving a prompt response which is maintained for approximately 48 hours.
Indications:
UVEDEXAVET can be used as an anti-inflammatory and anti-allergic agent, snake and insects bites in horses, cattle, dogs and cats and for the treatment of primary ketosis in cattle.
UVEDEXAVET can also be used to induce parturition in cattle.
UVEDEXAVET is suitable for intravenous use in the horse and is thus of particular benefit in cases needing emergency treatment.
Contraindications:
Except in emergency situations UVEDEXAVET should not be used in animals suffering from diabetes, chronic nephritis, renal disease, congestive heart failure,osteoporosis and in viral infections during the viraemic stage.
Warnings:
If the product is used for induction of parturition in cattle, then a high incidence of retained placentae may be experienced and possible subsequent metritis and/or subfertility.
Care should be taken when the product is used for the treatment of laminitis in horses, where there is the possibility that such treatment could worsen the condition.
The use of the product in horses for other conditions could induce laminitis and careful observation during the treatment period should be made.
USE DURING PREGNANCY:
Apart from the use to induce parturition in cattle, corticosteroids are not recommended for use in pregnant animals.
Administration in early pregnancy is known to have caused fetal abnormalities in laboratory animals.
Administration in late pregnancy may cause early parturition or abortion.
Use of the product in lactating cows may cause a reduction in milk yield.
Withdrawal Period:
Cattle:
Meat and offal: 8 days
Milk: 72 hours
Meat and offal: 8 days
Milk: 72 hours
Dosage and administration:
May be administered by intravenous or intramuscular injection in horses, and by intramuscular injection in cattle, dogs and cats.
The product may also be given by intra-articular injection in horses.
Horses, Cattle: 1.5 ml/50 kg
Dogs, Cats 0.5 ml/10 kg
Storage:
Store at temperature between (15- 25)°C, protect from direct sun light.